NSAIDs

Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in

27 Urinary bladder cancer prevention studies were performed with the nonsteroidal anti28 inflammatory drugs (NSAIDs) naproxen (a standard NSAID with a good cardiovascular profile), 29 sulindac, and their nitric oxide (NO) derivatives. Additionally, the effects of the ornithine 30 decarboxylase inhibitor, difluoromethylornithine (DFMO), alone or combined with a suboptimal 31 dose of naproxen or ...

NSAIDs as Cancer Preventive Agents NSAIDs as Cancer Preventive Agents

Introduction: Targeting of inflammatory states with non-steroidal anti-inflammatory drugs (NSAID’S) is an attractive proposition for cancer prevention. There is abundant epidemiological and experimental evidence that NSAID’S can inhibit tumour development in a number of organs and such drugs have given positive results in human intervention studies. It is hoped that problems with side effects c...

Pain Management beyond Nsaids

According to the International Association for the Study of Pain, pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Language is used to describe sensations and emotions, but it is not a prerequisite for feeling these; i.e. lack of ability to verbally communicate in no alters the perception of pain in h...

HELICOBACTER PYLORI AND NSAIDs

NSAIDs and balanced analgesia

Anaesthetists have changed their drug regimens several times in the last few decades. Today, anaesthesia is most frequently carried out with a "balanced" combination of agents to achieve optimal surgical anaesthesia and enhance recovery. Similarly, analgesia, one of the comerstones of anaesthesia, is increasingly considered with a combination of pharmacological agents and the term "balanced ana...